Premiership defender Nathan Brown and his twin brother Mitch, of the West Coast Eagles, will become the 12th set of twins in the game's history to reach a combined 150 games (provided one of the twins is selected to play this week).

Nathan has played 84 senior games since debuting in round one, 2008, while Mitch has notched 65 for West Coast since beginning in the first round of the previous season.

Both players were products of the 2006 National Draft. Nathan was recruited to Collingwood with the 10th selection and Mitch became an Eagle with pick No. 16. The twins are products of TAC Cup club North Ballarat.

The Browns follow in the footsteps of the Wakelins (513 games for Shane and Darryl), the Febeys (401 games for Steven and Matthew), the Scotts (383 games for Chris and Brad), the Selwoods (261 games for Adam and Troy), the Lonies (227 games for Nathan and Ryan), the Naismiths (211 games for Charlie and Wally), the Lords (196 games for Alistair and Stewart), the Clays (188 games for Bert and Ivor), the Lockwoods (167 games for Teddy and George), the Richardsons (157 games for Michael and Stephen) and the Atkins twins (151 games for Simon and Paul).