Collingwood midfielder Taylor Adams and forward Jamie Elliott both suffered low grade hamstring strains at training on Wednesday.
Neither will be available to play Adelaide on Friday night at Adelaide Oval.
Collingwood has a 12-day break between the encounter with the Crows and its next match, against Essendon on ANZAC Day.
Scans for both players this afternoon revealed minor strains. A return for Adams and Elliott to the full training program will be determined in the next week.